diff --git a/pkgs/development/python-modules/sanic/default.nix b/pkgs/development/python-modules/sanic/default.nix
index 1ec5ab87d83c..660ca5de80bf 100644
--- a/pkgs/development/python-modules/sanic/default.nix
+++ b/pkgs/development/python-modules/sanic/default.nix
@@ -73,9 +73,24 @@ buildPythonPackage rec {
   preCheck = ''
     # Some tests depends on sanic on PATH
     PATH="$out/bin:$PATH"
+    PYTHONPATH=$PWD:$PYTHONPATH
+
+    # needed for relative paths for some packages
+    cd tests
   '';
 
+  # uvloop usage is buggy
+  #SANIC_NO_UVLOOP = true;
+
+  pytestFlagsArray = [
+    "--asyncio-mode=auto"
+  ];
+
   disabledTests = [
+    # Lack of uvloop setup through fixtures
+    "test_create_asyncio_server"
+    "test_listeners_triggered_async"
+    "test_tls_options"
     # Tests are flaky
     "test_keep_alive_client_timeout"
     "test_check_timeouts_request_timeout"
@@ -103,6 +118,14 @@ buildPythonPackage rec {
     "test_version"
   ];
 
+  disabledTestPaths = [
+    # unable to create async loop
+    "test_app.py"
+    "test_asgi.py"
+    # occasionally hangs
+    "test_multiprocessing.py"
+  ];
+
   # avoid usage of nixpkgs-review in darwin since tests will compete usage
   # for the same local port
   __darwinAllowLocalNetworking = true;