diff --git a/pkgs/tools/X11/xpra/default.nix b/pkgs/tools/X11/xpra/default.nix
index 69f7dcb469af..21e37a2eb405 100644
--- a/pkgs/tools/X11/xpra/default.nix
+++ b/pkgs/tools/X11/xpra/default.nix
@@ -135,7 +135,6 @@ in buildPythonApplication rec {
     dbus-python
     gst-python
     idna
-    ipaddress
     lz4
     netifaces
     numpy
diff --git a/pkgs/tools/admin/azure-cli/default.nix b/pkgs/tools/admin/azure-cli/default.nix
index 01cb5081cf4f..b4d1d6dd7b76 100644
--- a/pkgs/tools/admin/azure-cli/default.nix
+++ b/pkgs/tools/admin/azure-cli/default.nix
@@ -159,7 +159,6 @@ py.pkgs.toPythonApplication (py.pkgs.buildAzureCliPackage {
     javaproperties
     jsondiff
     # urllib3[secure]
-    ipaddress
     # shell completion
     argcomplete
   ];
diff --git a/pkgs/tools/backup/duplicity/default.nix b/pkgs/tools/backup/duplicity/default.nix
index 7a6a34949204..95e29686f24e 100644
--- a/pkgs/tools/backup/duplicity/default.nix
+++ b/pkgs/tools/backup/duplicity/default.nix
@@ -78,15 +78,12 @@ pythonPackages.buildPythonApplication rec {
     idna
     pygobject3
     fasteners
-    ipaddress
     lockfile
     paramiko
     pyasn1
     pycrypto
     pydrive2
     future
-  ] ++ lib.optionals (!isPy3k) [
-    enum
   ];
 
   checkInputs = [
diff --git a/pkgs/tools/networking/dd-agent/5.nix b/pkgs/tools/networking/dd-agent/5.nix
index 744fd482ab18..57ab6ed97b90 100644
--- a/pkgs/tools/networking/dd-agent/5.nix
+++ b/pkgs/tools/networking/dd-agent/5.nix
@@ -18,7 +18,6 @@ let
           six
           requests
           websocket-client
-          ipaddress
           docker_pycreds
           uptime
         ] ++ lib.optionals (self.pythonOlder "3.7") [ backports_ssl_match_hostname ];