diff --git a/changelog.d/7321.misc b/changelog.d/7321.misc
new file mode 100644
index 000000000..a4b3e67af
--- /dev/null
+++ b/changelog.d/7321.misc
@@ -0,0 +1 @@
+Reduce logging verbosity for successful federation requests.
diff --git a/synapse/http/matrixfederationclient.py b/synapse/http/matrixfederationclient.py
index 6f1bb04d8..6b0a532c0 100644
--- a/synapse/http/matrixfederationclient.py
+++ b/synapse/http/matrixfederationclient.py
@@ -434,21 +434,27 @@ class MatrixFederationHttpClient(object):
                         logger.info("Failed to send request: %s", e)
                         raise_from(RequestSendFailed(e, can_retry=True), e)
 
-                    logger.info(
-                        "{%s} [%s] Got response headers: %d %s",
-                        request.txn_id,
-                        request.destination,
-                        response.code,
-                        response.phrase.decode("ascii", errors="replace"),
-                    )
-
                     incoming_responses_counter.labels(method_bytes, response.code).inc()
 
                     set_tag(tags.HTTP_STATUS_CODE, response.code)
 
                     if 200 <= response.code < 300:
+                        logger.debug(
+                            "{%s} [%s] Got response headers: %d %s",
+                            request.txn_id,
+                            request.destination,
+                            response.code,
+                            response.phrase.decode("ascii", errors="replace"),
+                        )
                         pass
                     else:
+                        logger.info(
+                            "{%s} [%s] Got response headers: %d %s",
+                            request.txn_id,
+                            request.destination,
+                            response.code,
+                            response.phrase.decode("ascii", errors="replace"),
+                        )
                         # :'(
                         # Update transactions table?
                         d = treq.content(response)