diff --git a/.github/workflows/tests.yml b/.github/workflows/tests.yml
index 21c9ee782..cb72e1a23 100644
--- a/.github/workflows/tests.yml
+++ b/.github/workflows/tests.yml
@@ -76,7 +76,7 @@ jobs:
     runs-on: ubuntu-latest
     strategy:
       matrix:
-        python-version: ["3.6", "3.7", "3.8", "3.9", "3.10"]
+        python-version: ["3.7", "3.8", "3.9", "3.10"]
         database: ["sqlite"]
         toxenv: ["py"]
         include:
@@ -85,9 +85,9 @@ jobs:
             toxenv: "py-noextras"
 
           # Oldest Python with PostgreSQL
-          - python-version: "3.6"
+          - python-version: "3.7"
             database: "postgres"
-            postgres-version: "9.6"
+            postgres-version: "10"
             toxenv: "py"
 
           # Newest Python with newest PostgreSQL
@@ -167,7 +167,7 @@ jobs:
     runs-on: ubuntu-latest
     strategy:
       matrix:
-        python-version: ["pypy-3.6"]
+        python-version: ["pypy-3.7"]
 
     steps:
       - uses: actions/checkout@v2
@@ -291,8 +291,8 @@ jobs:
     strategy:
       matrix:
         include:
-          - python-version: "3.6"
-            postgres-version: "9.6"
+          - python-version: "3.7"
+            postgres-version: "10"
 
           - python-version: "3.10"
             postgres-version: "14"
diff --git a/changelog.d/11595.misc b/changelog.d/11595.misc
new file mode 100644
index 000000000..57e54db5a
--- /dev/null
+++ b/changelog.d/11595.misc
@@ -0,0 +1 @@
+Drop EOL python 3.6 and postgres 9.6 from CI.
\ No newline at end of file
diff --git a/tox.ini b/tox.ini
index cfe6a0694..2ffca14b2 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,5 +1,5 @@
 [tox]
-envlist = packaging, py36, py37, py38, py39, check_codestyle, check_isort
+envlist = packaging, py37, py38, py39, py310, check_codestyle, check_isort
 
 # we require tox>=2.3.2 for the fix to https://github.com/tox-dev/tox/issues/208
 minversion = 2.3.2