diff --git a/changelogs/fragments/ansible-test-pylint-typed-ast.yml b/changelogs/fragments/ansible-test-pylint-typed-ast.yml
new file mode 100644
index 00000000000..3590e89f5ee
--- /dev/null
+++ b/changelogs/fragments/ansible-test-pylint-typed-ast.yml
@@ -0,0 +1,2 @@
+minor_changes:
+  - ansible-test - Update ``typed-ast`` constraint to version 1.4.3 for compatibility with Python 3.10.
diff --git a/test/lib/ansible_test/_data/requirements/sanity.pylint.txt b/test/lib/ansible_test/_data/requirements/sanity.pylint.txt
index ecdc2197d2a..612cb2cb428 100644
--- a/test/lib/ansible_test/_data/requirements/sanity.pylint.txt
+++ b/test/lib/ansible_test/_data/requirements/sanity.pylint.txt
@@ -8,5 +8,5 @@ lazy-object-proxy == 1.4.3
 mccabe == 0.6.1
 six  # not frozen due to usage outside sanity tests
 toml == 0.10.2
-typed-ast == 1.4.2
+typed-ast == 1.4.3
 wrapt == 1.12.1