diff --git a/x-pack/plugins/fleet/public/applications/fleet/sections/agent_policy/edit_package_policy_page/index.tsx b/x-pack/plugins/fleet/public/applications/fleet/sections/agent_policy/edit_package_policy_page/index.tsx
index 71dfb610a915..f082a2931681 100644
--- a/x-pack/plugins/fleet/public/applications/fleet/sections/agent_policy/edit_package_policy_page/index.tsx
+++ b/x-pack/plugins/fleet/public/applications/fleet/sections/agent_policy/edit_package_policy_page/index.tsx
@@ -283,6 +283,7 @@ export const EditPackagePolicyForm = memo<{
   // Update package policy method
   const updatePackagePolicy = useCallback(
     (updatedFields: Partial<UpdatePackagePolicy>) => {
+      setIsEdited(true);
       const newPackagePolicy = {
         ...packagePolicy,
         ...updatedFields,
@@ -343,6 +344,7 @@ export const EditPackagePolicyForm = memo<{
   }, [from, getHref, packageInfo, policyId]);
 
   // Save package policy
+  const [isEdited, setIsEdited] = useState(false);
   const [formState, setFormState] = useState<PackagePolicyFormState>('INVALID');
   const savePackagePolicy = async () => {
     setFormState('LOADING');
@@ -582,7 +584,8 @@ export const EditPackagePolicyForm = memo<{
                       <EuiButton
                         onClick={onSubmit}
                         isLoading={formState === 'LOADING'}
-                        disabled={formState !== 'VALID'}
+                        // Allow to save only if the package policy is upgraded or had been edited
+                        disabled={formState !== 'VALID' || (!isEdited && !isUpgrade)}
                         iconType="save"
                         color="primary"
                         fill