diff --git a/x-pack/plugins/security_solution/public/detections/components/host_isolation/use_host_isolation_action.tsx b/x-pack/plugins/security_solution/public/detections/components/host_isolation/use_host_isolation_action.tsx
index 24bc670a13ec..4282a584ea9f 100644
--- a/x-pack/plugins/security_solution/public/detections/components/host_isolation/use_host_isolation_action.tsx
+++ b/x-pack/plugins/security_solution/public/detections/components/host_isolation/use_host_isolation_action.tsx
@@ -80,12 +80,13 @@ export const useHostIsolationAction = ({
       isIsolationAllowed &&
       isEndpointAlert &&
       isolationSupported &&
-      isHostIsolationPanelOpen === false
+      isHostIsolationPanelOpen === false &&
+      loadingHostIsolationStatus === false
         ? [
             <EuiContextMenuItem
               key="isolate-host-action-item"
               data-test-subj="isolate-host-action-item"
-              disabled={loadingHostIsolationStatus || agentStatus === HostStatus.UNENROLLED}
+              disabled={agentStatus === HostStatus.UNENROLLED}
               onClick={isolateHostHandler}
             >
               {isolateHostTitle}